Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24599545 | 0.88 | GABRA1 (0.30) | GABRA1GABRB1 | |
| SCHEMBL24599547 | 0.88 | GABRA1 (0.30) | GABRA1GABRB1 | |
| SCHEMBL24462661 | 0.83 | BCL2 (0.31) | GABRA1GABRB1 | |
| SCHEMBL24599550 | 0.83 | GABRA1 (0.30) | GABRA1GABRB1 | |
| SCHEMBL23848704 | 0.83 | GABRA1 (0.30) | GABRA1GABRB1 | |
| SCHEMBL23848707 | 0.83 | GABRA1 (0.32) | GABRA1GABRB1 | |
| SCHEMBL23569457 | 0.83 | GABRA1 (0.32) | GABRA1GABRB1 | |
| SCHEMBL23569144 | 0.83 | GABRA1 (0.32) | GABRA1GABRB1 | |
| SCHEMBL24599546 | 0.80 | TAS1R3 (0.31) | — | |
| SCHEMBL24611074 | 0.80 | GABRA1 (0.33) | GABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213109-A1 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO LTD (CN) | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213109-A1 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | GABRA1 4281/4885GABRB1 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.