Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27696619 | 0.87 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1TDP1KMT2AMAPK1 | |
| SCHEMBL7060682 | 0.87 | MMP8 (0.56) | MMP8ALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL27801418 | 0.87 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1LMNATDP1KMT2A | |
| SCHEMBL11195047 | 0.86 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1LMNATDP1KMT2A | |
| SCHEMBL27748674 | 0.86 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1LMNATDP1KMT2A | |
| SCHEMBL27452191 | 0.86 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1LMNATDP1KMT2A | |
| Hydrochloric Acid SCHEMBL4263027 | 0.86 | ALDH1A1 (0.50) | MMP8ALDH1A1L3MBTL1TDP1KMT2A | |
| Hydrochloric Acid SCHEMBL4263030 | 0.86 | ALDH1A1 (0.50) | MMP8ALDH1A1L3MBTL1TDP1KMT2A | |
| SCHEMBL27371886 | 0.85 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1LMNATDP1KMT2A | |
| Hydrochloric Acid SCHEMBL27576626 | 0.85 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1LMNATDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213060-A1 | Crystal Form of Quinazolinone Compound and Preparation Method Therefor | Luoxin Healthcare Science and Technology Development (Beijing) Ltd. (CN) | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213060-A1 | Crystal Form of Quinazolinone Compound and Preparation Method Therefor | WEE1, PIK3CA, PIK3CD | MMP8 2957/4885ALDH1A1 3049/4885L3MBTL1 4771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.