SCHEMBL7060682

SCHEMBL7060682

CCOC(=O)C(CC)C(=O)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.56
ALDH1A1 P00352 6/20 0.55
L3MBTL1 Q9Y468 4/20 0.52
LMNA P02545 2/20 0.52
TDP1 Q9NUW8 3/20 0.50
KMT2A Q03164 3/20 0.49
MAPK1 P28482 2/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
PIN1 Q13526 1/20 0.47
TP53 P04637 1/20 0.47
NPC1 O15118 3/20 0.47
RAB9A P51151 2/20 0.47
MEN1 O00255 1/20 0.46
HSD17B10 Q99714 2/20 0.46
NPY1R P25929 1/20 0.46
NPY2R P49146 1/20 0.46
POLB P06746 1/20 0.45
CYP3A4 P08684 1/20 0.45
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14744437 0.95 ALDH1A1 (0.60) MMP8ALDH1A1L3MBTL1LMNATDP1
SCHEMBL7391865 0.89 ALDH1A1 (0.58) MMP8ALDH1A1L3MBTL1LMNATDP1
SCHEMBL14873821 0.89 ALDH1A1 (0.58) MMP8ALDH1A1L3MBTL1LMNATDP1
SCHEMBL27455586 0.89 ALDH1A1 (0.50) MMP8ALDH1A1L3MBTL1LMNATDP1
SCHEMBL24599861 0.87 MMP8 (0.54) MMP8ALDH1A1L3MBTL1LMNATDP1
SCHEMBL27657518 0.87 ALDH1A1 (0.51) MMP8ALDH1A1L3MBTL1LMNATDP1
SCHEMBL10708405 0.86 ALDH1A1 (0.59) MMP8ALDH1A1L3MBTL1LMNATDP1
SCHEMBL10962901 0.86 MEN1 (0.50) MMP8ALDH1A1LMNATDP1KMT2A
SCHEMBL28765985 0.86 MMP8 (0.50) MMP8ALDH1A1L3MBTL1LMNATDP1
SCHEMBL12674439 0.86 ALDH1A1 (0.58) MMP8ALDH1A1L3MBTL1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110167580-A Pharmaceutical composition and method for treating cancer 迪美公司 2019-08-23 CN claimed
CN-106608939-B The preparation method of catalytic component for olefinic polymerization 中国石油化工股份有限公司 2019-08-20 CN claimed
CN-110114053-A Oil-in-water type emulsion composition 花王株式会社 2019-08-09 CN claimed
CN-110062633-A Tyrosine derivatives and compositions comprising the same 迪美公司 2019-07-26 CN claimed
CN-106608940-B The preparation method of catalytic component for olefinic polymerization 中国石油化工股份有限公司 2019-06-28 CN claimed
CN-109562116-A Protona and protona derivative and promotor in cancer treatment 迪美公司 2019-04-02 CN claimed
CN-109195601-A Pharmaceutical composition for treating cancer 迪美公司 2019-01-11 CN claimed
CN-108795072-A A kind of the poisonous substance inhibitor and its application method of the sulfenyl cementitious matter substituting part pitch 太原理工大学 2018-11-13 CN claimed
CN-104558290-B One kind being used for catalyst component for olefin polymerization and catalyst 中国石油化工股份有限公司 2018-11-02 CN claimed
CN-105848771-B High-speed centrifugal mixing arrangement and application method 迪美公司 2018-07-10 CN claimed
CN-102757379-A Preparation method of alvimopan SHANGHAI HAOYUAN BIOLOG MEDICAL TECHNOLOGY CO LTD 2012-10-31 CN claimed
CN-101215246-B Method for preparing alpha-ketoxime acid ester UNIV HEBEI SCIENCE & TECH 2010-08-18 CN claimed
CN-101602728-A 3 of N-substituted benzene ring, 5-pyrazodione compounds and its production and use UNIV ZHENGZHOU (CN) 2009-12-16 CN claimed
CN-101215246-A Method for preparing alpha-ketoxime acid ester UNIV HEBEI SCIENCE & TECH (CN) 2008-07-09 CN claimed
CN-101163659-A Antioxidants MERCK PATENT GMBH (DE) 2008-04-16 CN claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
CN-1233241-A Propionic acid derivatives and uses thereof JAPAN TOBACCO INC (JP) 1999-10-27 CN claimed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
CN-85102275-A NEW PROCESS FOR SYNTHESIZING PROPAFENONE 1985-11-10 CN claimed