SCHEMBL24599863

SCHEMBL24599863

FC(OC(F)(F)C(F)(F)C(F)(F)F)C(F)(F)Oc1ccc2ccccc2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.36
CYP2A6 P11509 2/20 0.36
AGXT P21549 2/20 0.33
GABBR2 O75899 1/20 0.33
GABBR1 Q9UBS5 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPK1 P28482 1/20 0.33
PPARG P37231 3/20 0.32
PPARA Q07869 3/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
ALOX5 P09917 1/20 0.32
KIF11 P52732 1/20 0.31
GAA P10253 1/20 0.31
RCE1 Q9Y256 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
PTPN1 P18031 2/20 0.31
PTPN7 P35236 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24599949 0.87 CYP1A2 (0.33) CYP1A2CYP2A6AGXTGABBR2GABBR1
SCHEMBL22746177 0.86 CYP2A6 (0.36) CYP1A2CYP2A6TDP1KDM4E
SCHEMBL13559079 0.83 ALDH1A1 (0.35)
SCHEMBL10590774 0.77 ALDH1A1 (0.33)
SCHEMBL22746167 0.77 CYP1A2 (0.31) CYP1A2CYP2A6
SCHEMBL15673809 0.75 PIM1 (0.39) TDP1
SCHEMBL22746169 0.74 CETP (0.30)
SCHEMBL5366998 0.73 ALDH1A1 (0.32)
SCHEMBL15675340 0.73 PPARG (0.39) PPARGPPARAPTPN1MEN1KMT2A
SCHEMBL9189366 0.73 MEN1 (0.40) TDP1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213039-A1 PYRIDINIUM SALTS AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213039-A1 PYRIDINIUM SALTS AND PEST CONTROL AGENT ZYX, PNPO, PRDX1 CYP1A2 499/4885CYP2A6 556/4885AGXT 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.