SCHEMBL5366998

SCHEMBL5366998

C=Cc1ccc(OC(F)(F)C(F)OC(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15675988 0.90
SCHEMBL15711740 0.88 ALDH1A1 (0.31) ALDH1A1TSHRHSD17B10
SCHEMBL15673809 0.83 PIM1 (0.39)
SCHEMBL5360002 0.82 TRPA1 (0.32)
SCHEMBL13559079 0.80 ALDH1A1 (0.35) ALDH1A1TSHRHSD17B10
SCHEMBL9823923 0.79 ALDH1A1 (0.44) ALDH1A1TSHRHSD17B10
SCHEMBL15675340 0.77 PPARG (0.39) ALDH1A1TSHRHSD17B10
SCHEMBL15675867 0.76 DRD1 (0.35) ALDH1A1TSHRHSD17B10
SCHEMBL22721355 0.75 TSHR (0.60) ALDH1A1TSHRHSD17B10
SCHEMBL13399345 0.74 ALDH1A1 (0.39) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070299276-A1 Preparation of fluoroalkoxystyrenes E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-27 US disclosed
US-20070299276-A1 Preparation of fluoroalkoxystyrenes E. I. DU PONT DE NEMOURS AND COMPANY 2007-12-27 US disclosed
WO-2007149449-A2 PREPARATION OF FLUOROALKOXYSTYRENES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070299276-A1 Preparation of fluoroalkoxystyrenes LSS, CYP2F1, PFAS ALDH1A1 746/4885TSHR 2571/4885HSD17B10 318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.