SCHEMBL24600019

SCHEMBL24600019

COC(=O)CC1=CC(=S)C(=O)C=C1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
HSP90AB1 P08238 1/20 0.38
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
ALDH1A1 P00352 4/20 0.35
KMT2A Q03164 3/20 0.35
LMNA P02545 2/20 0.35
HTT P42858 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GAA P10253 4/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
MEN1 O00255 2/20 0.33
GFER P55789 1/20 0.33
TSHR P16473 2/20 0.32
SETD7 Q8WTS6 1/20 0.32
CMA1 P23946 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10702537 0.71 MAPT (0.38) MAPTHSP90AB1CYP4F2CYP4A11ALDH1A1
SCHEMBL10685821 0.70 HSP90AB1 (0.37) MAPTHSP90AB1CYP4F2CYP4A11ALDH1A1
SCHEMBL28652878 0.68 HSP90AB1 (0.38) MAPTHSP90AB1CYP4F2CYP4A11ALDH1A1
SCHEMBL968532 0.63 HSP90AB1 (0.40) MAPTHSP90AB1CYP4F2CYP4A11ALDH1A1
SCHEMBL23349282 0.62 HSP90AB1 (0.39) MAPTHSP90AB1CYP4F2CYP4A11ALDH1A1
SCHEMBL27947107 0.62 HSP90AB1 (0.47) MAPTHSP90AB1CYP4F2CYP4A11ALDH1A1
SCHEMBL5751054 0.61 HSP90AB1 (0.42) MAPTHSP90AB1CYP4F2CYP4A11ALDH1A1
SCHEMBL10702536 0.61 ALDH1A1 (0.42) MAPTALDH1A1KMT2ALMNAHSD17B10
SCHEMBL21891794 0.61 HSP90AB1 (0.75) MAPTHSP90AB1CYP4F2CYP4A11ALDH1A1
SCHEMBL4113212 0.61 CYP4F2 (0.76) MAPTHSP90AB1CYP4F2CYP4A11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132763-A1 FUCOSYLTRANSFERASE SPECIFIC INHIBITION USING FUCOSE MIMETICS UNIVERSITY OF FLORENCE (IT) 2023-05-04 US disclosed
US-20230132763-A1 FUCOSYLTRANSFERASE SPECIFIC INHIBITION USING FUCOSE MIMETICS UNIVERSITY OF FLORENCE (IT) 2023-05-04 US disclosed
US-20220211734-A1 FUCOSYLTRANSFERASE SPECIFIC INHIBITION USING FUCOSE MIMETICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230132763-A1 FUCOSYLTRANSFERASE SPECIFIC INHIBITION USING FUCOSE MIMETICS FUCA1, FUCA2, B4GALT1 MAPT 2520/4885HSP90AB1 2680/4885CYP4F2 756/4885
US-20220211734-A1 FUCOSYLTRANSFERASE SPECIFIC INHIBITION USING FUCOSE MIMETICS FUCA1, FUCA2, B4GALT1 MAPT 2520/4885HSP90AB1 2680/4885CYP4F2 756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.