Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20392315 | 0.85 | HSP90AB1 (0.33) | HSP90AB1CYP4F2CYP4A11ALDH1A1HSD17B10 | |
| SCHEMBL23349282 | 0.83 | HSP90AB1 (0.39) | HSP90AB1CYP4F2CYP4A11ALDH1A1HSD17B10 | |
| SCHEMBL5751054 | 0.81 | HSP90AB1 (0.42) | HSP90AB1CYP4F2CYP4A11ALDH1A1HSD17B10 | |
| SCHEMBL30292110 | 0.81 | GSK3A (0.40) | ALDH1A1HSD17B10KMT2AGAASMN1; SMN2 | |
| SCHEMBL1055501 | 0.81 | TSHR (0.41) | ALDH1A1HSD17B10MAPTKMT2AHTT | |
| SCHEMBL23470149 | 0.78 | MYC (0.32) | ALDH1A1HSD17B10GAAHPGDALOX15 | |
| SCHEMBL20730313 | 0.76 | HSP90AB1 (0.33) | HSP90AB1CYP4F2CYP4A11 | |
| SCHEMBL28652878 | 0.74 | HSP90AB1 (0.38) | HSP90AB1CYP4F2CYP4A11ALDH1A1HSD17B10 | |
| SCHEMBL19886689 | 0.73 | HSD11B1 (0.30) | — | |
| SCHEMBL10685821 | 0.73 | HSP90AB1 (0.37) | HSP90AB1CYP4F2CYP4A11ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507453-B2 | Anti-penicillin resistant pneumococci agent and novel 16-membered macrolide derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8389572-B2 | Therapeutic delivery of carbon monoxide | HEMOCORM LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-8389572-B2 | Therapeutic delivery of carbon monoxide | HEMOCORM LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-8389572-B2 | Therapeutic delivery of carbon monoxide | HEMOCORM LIMITED (GB) | 2013-03-05 | — | — | US | disclosed |
| US-20120015896-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | MICROBIAL CHEMISTRY RESEARCH FOUNDATION | 2012-01-19 | — | — | US | disclosed |
| US-20110015263-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | HEMOCORM LIMITED | 2011-01-20 | — | — | US | disclosed |
| US-20110015263-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | HEMOCORM LIMITED | 2011-01-20 | — | — | US | disclosed |
| US-20110015263-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | HEMOCORM LIMITED | 2011-01-20 | — | — | US | disclosed |
| WO-2007085806-A2 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | HEMOCORM LIMITED (GB) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015896-A1 | Anti-Penicillin Resistant Pneumococci Agent and Novel 16-Membered Macrolide Derivative | PWWP2B, BRWD1, BAZ1A | HSP90AB1 1689/4885CYP4F2 4616/4885CYP4A11 3942/4885 |
| US-20110015263-A1 | THERAPEUTIC DELIVERY OF CARBON MONOXIDE | MB, TFRC, CYC1 | HSP90AB1 945/4885CYP4F2 695/4885CYP4A11 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.