Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 10/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 3/20 | 0.41 |
| ▸ | IKBKB | O14920 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | INSR | P06213 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29691588 | 0.83 | ENPP1 (0.53) | NUDT1PRKCICHUKIKBKBMAPK8 | |
| SCHEMBL24600506 | 0.83 | ENPP1 (0.53) | NUDT1PRKCICHUKIKBKBMAPK8 | |
| Hydrochloric Acid SCHEMBL29691657 | 0.82 | ENPP1 (0.54) | NUDT1PRKCICHUKIKBKBMAPK8 | |
| Hydrochloric Acid SCHEMBL26680014 | 0.82 | ENPP1 (0.54) | NUDT1PRKCICHUKIKBKBMAPK8 | |
| SCHEMBL26679983 | 0.81 | NUDT1 (0.43) | NUDT1PRKCICHUKIKBKBMAPK8 | |
| SCHEMBL24600955 | 0.81 | CDK9 (0.47) | NUDT1PRKCICHUKIKBKBMAPK8 | |
| Hydrochloric Acid SCHEMBL26680010 | 0.81 | NUDT1 (0.42) | NUDT1PRKCICHUKIKBKBMAPK8 | |
| SCHEMBL24600623 | 0.80 | NUDT1 (0.40) | NUDT1PRKCICHUKIKBKBMAPK8 | |
| SCHEMBL24600967 | 0.78 | PRKCI (0.47) | NUDT1PRKCICHUKIKBKBMAPK8 | |
| SCHEMBL29248795 | 0.77 | CHUK (0.48) | NUDT1PRKCICHUKIKBKBMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276100-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | Txinno Bioscience Inc. (KR) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022146022-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | 주식회사 티씨노바이오사이언스 | 2022-07-07 | — | — | WO | disclosed |