SCHEMBL2460073

SCHEMBL2460073

CSc1[c]c2ccccc2cc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10469539 0.82 CYP2A6 (0.34) CYP1A2TDP1
SCHEMBL2456769 0.78
SCHEMBL2464471 0.78 ELANE (0.33) CYP1A2
SCHEMBL2460977 0.78 POLB (0.33)
SCHEMBL1127496 0.75 HPGD (0.39)
SCHEMBL17288504 0.74
SCHEMBL5829791 0.72
SCHEMBL29278063 0.72 AR (0.33)
SCHEMBL2454334 0.71 PTGS2 (0.39)
SCHEMBL5829792 0.71 MAP2K7 (0.39) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040116703-A1 8-Azabicyclo[3.2.1]oct-2-ene and -octane derivatives technical field NEUROSEARCH A/S 2004-06-17 US claimed
US-6680328-B2 CHOLINERGIC LIGANDS OF NICOTINIC ACETYL CHOLINE RECEPTORS FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, SMOOTH MUSCLE CONTRACTION DISORDERS, ENDOCRINE DISEASES/DISORDERS, NEURODEGENERATION, INFLAMMATION, PAIN, AND DRUG WITHDRAWAL NEUROSEARCH A/S (DK) 2004-01-20 US claimed
US-20020035122-A1 8-azabicyclo[3.2.1]oct-2-ene and -octane derivatives ANIONA APS (DK) 2002-03-21 US claimed
EP-1133494-A1 8-AZABICYCLO 3.2.1]OCT-2-ENE AND -OCTANE DERIVATIVES NEUROSEARCH A/S (DK) 2001-09-19 EP claimed
WO-2000032600-A1 8-AZABICYCLO[3.2.1]OCT-2-ENE AND -OCTANE DERIVATIVES NEUROSEARCH A/S (DK) 2000-06-08 WO claimed
WO-2024135508-A1 COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, PHOTOSENSOR AND SOLID-STATE IMAGING DEVICE 三菱瓦斯化学株式会社 2024-06-27 WO disclosed
WO-2024043246-A1 ANION EXCHANGE-TYPE POLYMER ELECTROLYTE MEMBRANE, WATER ELECTROLYSIS DEVICE, CARBON DIOXIDE ELECTROLYSIS DEVICE, FUEL CELL, AND PRODUCTION METHOD FOR ANION EXCHANGE-TYPE POLYMER ELECTROLYTE MEMBRANE 三井化学株式会社 2024-02-29 WO disclosed
WO-2023167234-A1 COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, PHOTOSENSOR AND SOLID-STATE IMAGING DEVICE 三菱瓦斯化学株式会社 2023-09-07 WO disclosed
CN-114616228-A Compound, polymerizable composition, polymer, hologram recording medium, optical material, and optical member 三菱化学株式会社 2022-06-10 CN disclosed
CN-113195481-A Compound and organic light emitting device including the same 株式会社LG化学 2021-07-30 CN disclosed
CN-113166133-A Compound and organic light emitting device including the same 株式会社LG化学 2021-07-23 CN disclosed
US-8012362-B2 Electromagnetic shielding light-transmitting member and method for manufacturing same TOPPAN PRINTING CO., LTD. (JP) 2011-09-06 US disclosed
US-4471068-A Process and catalyst for preparation of polyphenylene oxide GENERAL ELECTRIC COMPANY (US) 1984-09-11 US disclosed
EP-0116399-A2 Dithiophosphorus/amine salts and aqueous compositions containing same The Lubrizol Corporation (US) 1984-08-22 EP disclosed
US-4186157-A Phosphorus-containing reaction mixture THE LUBRIZOL CORPORATION (US) 1980-01-29 US disclosed
US-RE30142-E FOR LUBRICANTS THE LUBRIZOL CORPORATION (US) 1979-11-06 US disclosed
US-4129510-A Sulfur-containing compounds and lubricants and fuels containing them THE LUBRIZOL CORPORATION (US) 1978-12-12 US disclosed
US-4081387-A Phosphorus-containing lubricating compositions THE LUBRIZOL CORPORATION (US) 1978-03-28 US disclosed
US-4070385-A HYDRAULIC FLUID ADDITIVES THE LUBRIZOL CORPORATION (US) 1978-01-24 US disclosed
US-4026812-A HYDRAULIC FLUIDS, OIL IN WATER EMULSIONS THE LUBRIZOL CORPORATION (US) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035122-A1 8-azabicyclo[3.2.1]oct-2-ene and -octane derivatives CHRNA2, CHRNA7, CHRNA10 CYP1A2 662/4885TDP1 665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.