Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.63 |
| ▸ | NT5E | P21589 | 12/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.54 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.54 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.54 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19370259 | 0.91 | ACHE (0.66) | ACHENT5EALDH1A1LMNATP53 | |
| SCHEMBL24078860 | 0.91 | ACHE (0.66) | ACHENT5EALDH1A1LMNATP53 | |
| SCHEMBL1120610 | 0.90 | ACHE (0.65) | ACHENT5EALDH1A1LMNATP53 | |
| SCHEMBL1120608 | 0.90 | ACHE (0.65) | ACHENT5EALDH1A1LMNATP53 | |
| SCHEMBL1120612 | 0.90 | ACHE (0.65) | ACHENT5EALDH1A1LMNATP53 | |
| SCHEMBL24601162 | 0.90 | ALDH1A1 (0.70) | ACHENT5EALDH1A1LMNATP53 | |
| SCHEMBL1120509 | 0.88 | ACHE (0.62) | ACHENT5EALDH1A1LMNATP53 | |
| SCHEMBL1120513 | 0.88 | ACHE (0.62) | ACHENT5EALDH1A1LMNATP53 | |
| SCHEMBL1120510 | 0.88 | ACHE (0.62) | ACHENT5EALDH1A1LMNATP53 | |
| SCHEMBL23982458 | 0.87 | PRKAB2 (0.68) | ACHENT5EALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273153-A1 | ADENOSINE A3 RECEPTOR AGONISTS, PREPARATION METHODS AND USES THEREOF | Zhejiang Vimgreen Pharmaceuticals, Ltd (CN) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022143740-A1 | ADENOSINE A3 RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江春禾医药科技有限公司 | 2022-07-07 | — | — | WO | disclosed |