Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | CD99 | P14209 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24601294 | 1.00 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL24601293 | 1.00 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL24601056 | 0.84 | ADORA2A (0.37) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL24601058 | 0.84 | ADORA2A (0.37) | PI4KAPI4K2BPI4K2API4KBADORA1 | |
| SCHEMBL24601057 | 0.82 | ADORA3 (0.46) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL307825 | 0.82 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL260752 | 0.80 | PI4KA (0.69) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL2294904 | 0.79 | PI4KA (0.66) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL260760 | 0.78 | PI4KA (0.59) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL2291671 | 0.77 | PI4KA (0.80) | PI4KAPI4K2BPI4K2API4KBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143740-A1 | ADENOSINE A3 RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江春禾医药科技有限公司 | 2022-07-07 | — | — | WO | disclosed |