Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.50 |
| ▸ | NT5E | P21589 | 10/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.47 |
| ▸ | CD99 | P14209 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24601222 | 0.84 | PDE4D (0.52) | ADORA3NT5ECA1CA2CA4 | |
| SCHEMBL20333764 | 0.84 | PDE4D (0.52) | ADORA3NT5ECA1CA2CA4 | |
| SCHEMBL12826793 | 0.73 | PDE4D (0.55) | ADORA3NT5EDNMT1DNMT3BCD99 | |
| SCHEMBL23586006 | 0.73 | PDE4D (0.55) | ADORA3NT5ECD99CA1CA2 | |
| SCHEMBL20333318 | 0.72 | PDE4D (0.52) | ADORA3NT5ECD99CA1CA2 | |
| SCHEMBL24600770 | 0.71 | ADORA3 (0.51) | ADORA3NT5EADORA2AADORA1 | |
| SCHEMBL20334131 | 0.70 | NT5E (0.53) | ADORA3NT5ECD99CA1CA2 | |
| SCHEMBL19157474 | 0.70 | ADORA3 (0.67) | ADORA3NT5EDNMT1CA1CA2 | |
| SCHEMBL22757359 | 0.70 | ADORA3 (0.52) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL12746571 | 0.70 | PDE4D (0.68) | ADORA3NT5EDNMT1DNMT3BCD99 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022143740-A1 | ADENOSINE A3 RECEPTOR AGONIST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江春禾医药科技有限公司 | 2022-07-07 | — | — | WO | disclosed |