Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.41 |
| ▸ | IARS1 | P41252 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22757488 | 0.90 | ADORA3 (0.49) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL22757466 | 0.78 | ADORA3 (0.45) | ADORA3ADORA1ADORA2A | |
| SCHEMBL22757471 | 0.77 | ADORA3 (0.41) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL24600770 | 0.74 | ADORA3 (0.51) | ADORA3ADORA1ADORA2A | |
| SCHEMBL23585883 | 0.71 | ADORA3 (0.46) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL22750501 | 0.70 | ADORA3 (0.61) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL14069237 | 0.70 | ADORA3 (0.64) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL24601458 | 0.70 | ADORA3 (0.50) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL19837865 | 0.68 | ADORA3 (0.69) | ADORA3ADORA1ADORA2AADORA2BIARS1 | |
| SCHEMBL4805543 | 0.67 | LMNA (0.65) | ADORA3ADORA1ADORA2AIARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247546-A1 | ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE | BIOINTERVENE, INC. (US) | 2020-12-10 | — | — | WO | disclosed |