SCHEMBL24601505

SCHEMBL24601505

c1cc(-c2cccc3oc4ccccc4c23)c(-c2ccc3c4c5c6ccccc6n6c7cc(-c8c(-c9cccc%10oc%11ccccc%11c9%10)cccc8-c8cccc9oc%10ccccc%10c89)ccc7c(c7c8ccccc8n(c3c2)c74)c56)c(-c2cccc3oc4ccccc4c23)c1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33
AHR P35869 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
BACE1 P56817 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601808 0.95 PLA2G2A (0.32) ALOX5BACE1CA1CA2
SCHEMBL24601525 0.94 ALOX5 (0.34) ALOX5L3MBTL1BACE1ALDH1A1CA1
SCHEMBL24601806 0.91 ALOX5 (0.36) ALOX5AHRBACE1KDM4EMEN1
SCHEMBL22178726 0.91 ALOX5 (0.38) ALOX5AHRL3MBTL1BACE1KDM4E
SCHEMBL24601807 0.89 PLA2G2A (0.35) ALOX5BACE1HPGDCA1CA2
SCHEMBL24601410 0.89 ALOX5 (0.36) ALOX5AHRBACE1KDM4EMEN1
SCHEMBL24601810 0.86 ALOX5 (0.36) ALOX5BACE1ALDH1A1
SCHEMBL24601679 0.86 CDK4 (0.34)
SCHEMBL22178596 0.86 ALOX5 (0.38) ALOX5AHRL3MBTL1BACE1KDM4E
SCHEMBL24601794 0.84 PLA2G2A (0.39) ALOX5BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 ALOX5 2351/4885AHR 4529/4885L3MBTL1 2377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.