SCHEMBL24601807

SCHEMBL24601807

c1ccc(-c2cccc(-c3cccc4oc5ccccc5c34)c2-c2ccc3c(c2)c2c4c5ccccc5n5c6ccc(-c7c(-c8ccccc8)cccc7-c7cccc8oc9ccccc9c78)cc6c(c6c7ccccc7n3c62)c45)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.35
PLA2G4A P47712 3/20 0.35
PLA2G10 O15496 1/20 0.35
ALOX5 P09917 1/20 0.32
BACE1 P56817 1/20 0.32
CDC14B O60729 1/20 0.31
CDC14A Q9UNH5 1/20 0.31
GABRP O00591 1/20 0.30
GABRD O14764 1/20 0.30
NPC1 O15118 1/20 0.30
CA12 O43570 1/20 0.30
TNKS O95271 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
TP53 P04637 1/20 0.30
ABCB1 P08183 1/20 0.30
CYP3A4 P08684 1/20 0.30
PARP1 P09874 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601525 0.95 ALOX5 (0.34) PLA2G2APLA2G4APLA2G10ALOX5BACE1
SCHEMBL24601808 0.94 PLA2G2A (0.32) PLA2G2APLA2G4APLA2G10ALOX5BACE1
SCHEMBL24601505 0.89 ALOX5 (0.33) ALOX5BACE1CA1CA2HPGD
SCHEMBL24601810 0.88 ALOX5 (0.36) PLA2G2APLA2G4APLA2G10ALOX5BACE1
SCHEMBL22178596 0.88 ALOX5 (0.38) PLA2G2APLA2G4APLA2G10ALOX5BACE1
SCHEMBL24601649 0.88 HSD17B10 (0.36) ALOX5ABCG2WEE1
SCHEMBL24601430 0.88 HSD17B10 (0.36) ALOX5ABCG2WEE1
SCHEMBL24601509 0.85 HSD17B10 (0.34) ALOX5SMN1; SMN2WEE1
SCHEMBL24601407 0.85 ALOX5 (0.40) PLA2G2APLA2G4APLA2G10ALOX5BACE1
SCHEMBL24601794 0.84 PLA2G2A (0.39) PLA2G2APLA2G4APLA2G10ALOX5BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 PLA2G2A 3834/4885PLA2G4A 4028/4885PLA2G10 3047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.