SCHEMBL24601530

SCHEMBL24601530

c1ccc(-c2cccc3c4c5c6cccc(-c7ccccc7)c6n6c7c(-c8ccccc8)cccc7c(c7c8cccc(-c9ccccc9)c8n(c23)c47)c56)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
MAPK1 P28482 1/20 0.41
LIMK1 P53667 4/20 0.38
CLK4 Q9HAZ1 2/20 0.38
MAP4K4 O95819 1/20 0.38
CSF1R P07333 1/20 0.38
FGFR1 P11362 1/20 0.38
PDGFRA P16234 1/20 0.38
LTK P29376 1/20 0.38
KDR P35968 1/20 0.38
MAPK8 P45983 1/20 0.38
CSNK1A1 P48729 1/20 0.38
CDK5 Q00535 1/20 0.38
ACVR1 Q04771 1/20 0.38
TNK2 Q07912 1/20 0.38
AURKB Q96GD4 1/20 0.38
DYRK1B Q9Y463 1/20 0.38
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
HSD17B10 Q99714 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601449 0.82 MAOB (0.37) LIMK1HSD17B10CDK4CCND1NPSR1
SCHEMBL24601445 0.81 HSD17B10 (0.34) ALDH1A1LIMK1CLK4MAP4K4CSF1R
SCHEMBL24601432 0.79 HSD17B10 (0.33) HSD17B10HPGDKDM4EMAPTKMT2A
SCHEMBL24601773 0.77 MAOB (0.34) LIMK1HSD17B10HPGDNPSR1KDM4E
SCHEMBL21472987 0.77 CDK4 (0.35) ALDH1A1LIMK1CLK4MAP4K4CSF1R
SCHEMBL21965187 0.76 KDM4E (0.42) ALDH1A1LIMK1CLK4MAP4K4CSF1R
SCHEMBL24601589 0.76 HSD17B10 (0.36) ALDH1A1LIMK1CLK4MAP4K4CSF1R
SCHEMBL21461880 0.75 MAPK14 (0.34) LIMK1CLK4MAP4K4CSF1RFGFR1
SCHEMBL2391683 0.74 ALDH1A1 (0.52) ALDH1A1MAPK1LIMK1CLK4MAP4K4
SCHEMBL21718027 0.73 KDM4E (0.38) LIMK1CLK4MAP4K4CSF1RFGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 ALDH1A1 3824/4885MAPK1 3245/4885LIMK1 1209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.