SCHEMBL24601445

SCHEMBL24601445

c1ccc(-c2cccc(-c3ccccc3)c2-c2cccc3c4c5c6ccccc6n6c7c(-c8c(-c9ccccc9)cccc8-c8ccccc8)cccc7c(c7c8ccccc8n(c23)c74)c56)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.34
HTR6 P50406 2/20 0.34
KDM4E B2RXH2 4/20 0.33
MAPK14 Q16539 1/20 0.33
TSHR P16473 1/20 0.33
LIMK1 P53667 2/20 0.32
MAP4K4 O95819 1/20 0.32
CSF1R P07333 1/20 0.32
FGFR1 P11362 1/20 0.32
PDGFRA P16234 1/20 0.32
LTK P29376 1/20 0.32
KDR P35968 1/20 0.32
MAPK8 P45983 1/20 0.32
CSNK1A1 P48729 1/20 0.32
CDK5 Q00535 1/20 0.32
ACVR1 Q04771 1/20 0.32
TNK2 Q07912 1/20 0.32
AURKB Q96GD4 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
DYRK1B Q9Y463 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24601432 0.83 HSD17B10 (0.33) HSD17B10HTR6KDM4ETSHRHPGD
SCHEMBL24601649 0.81 HSD17B10 (0.36) HSD17B10HTR6KDM4EMAPK14LIMK1
SCHEMBL24601430 0.81 HSD17B10 (0.36) HSD17B10HTR6KDM4EMAPK14LIMK1
SCHEMBL24601530 0.81 ALDH1A1 (0.41) HSD17B10KDM4ELIMK1MAP4K4CSF1R
SCHEMBL24601438 0.81 ALKBH5 (0.41) KDM4EMCL1MAPTMEN1KMT2A
SCHEMBL24601497 0.80 HSD17B10 (0.35) HSD17B10HTR6KDM4EMAPK14ENPP1
SCHEMBL24601423 0.80 HSD17B10 (0.35) HSD17B10HTR6KDM4EMAPK14ENPP1
SCHEMBL24601624 0.80 HSD17B10 (0.35) HSD17B10HTR6KDM4EMAPK14ENPP1
SCHEMBL24601589 0.80 HSD17B10 (0.36) HSD17B10HTR6KDM4EMAPK14LIMK1
SCHEMBL24601509 0.79 HSD17B10 (0.34) HSD17B10HTR6KDM4EMAPK14ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 HSD17B10 4661/4885HTR6 3265/4885KDM4E 3163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.