SCHEMBL24601619

SCHEMBL24601619

FC(F)(F)Oc1ccc2c(c1)c1c3c4ccccc4n4c5ccc(OC(F)(F)F)cc5c(c5c6ccccc6n2c51)c34

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.45
GPR3 P46089 2/20 0.39
ELANE P08246 2/20 0.39
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
HSD17B10 Q99714 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
NOD1 Q9Y239 1/20 0.36
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
ADRB2 P07550 1/20 0.35
SCN5A Q14524 1/20 0.35
TEAD1 P28347 1/20 0.34
TEAD4 Q15561 1/20 0.34
TEAD2 Q15562 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22178496 0.78 KIF11 (0.49) KIF11GPR3ALDH1A1MAPTL3MBTL1
SCHEMBL21570098 0.75 KDM4E (0.43) GPR3KDM4EMEN1ALDH1A1MAPT
SCHEMBL24601747 0.75 ATM (0.40) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL28192287 0.74 KIF11 (0.62) KIF11GPR3KDM4EHSD17B10CRHBP
SCHEMBL29643260 0.73 NPY5R (0.55) KDM4EMEN1ALDH1A1MAPTHPGD
SCHEMBL22178713 0.71 MAPT (0.41) KIF11GPR3KDM4EMEN1MAPT
SCHEMBL22178710 0.71 PGR (0.43) KIF11KDM4EMEN1ALDH1A1MAPT
SCHEMBL22178625 0.71 KIF11 (0.44) KIF11KDM4EMEN1ALDH1A1MAPT
SCHEMBL24601746 0.71 KIF11 (0.57) KIF11GPR3ALDH1A1MAPT
SCHEMBL22178499 0.70 TSPO (0.43) HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220213113-A1 NITROGEN-CONTAINING CONDENSED CYCLIC COMPOUNDS, FLUORESCENCE EMITTERS, ORGANIC ELECTROLUMINESCENT DEVICES, AND MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES NCL, NOC2L, NOLC1 KIF11 3347/4885GPR3 3843/4885ELANE 892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.