Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460433 | 1.00 | GPR119 (0.45) | GPR119KDM4EBLMALOX15ALDH1A1 | |
| SCHEMBL9717952 | 0.89 | GPR119 (0.47) | GPR119KDM4EBLMALOX15ALDH1A1 | |
| SCHEMBL16680417 | 0.87 | ABCB1 (0.48) | GPR119KDM4ERIPK1PKM | |
| SCHEMBL16681762 | 0.87 | ABCB1 (0.48) | GPR119KDM4ERIPK1PKM | |
| SCHEMBL11995175 | 0.85 | ALDH1A1 (0.44) | GPR119KDM4EBLMALOX15ALDH1A1 | |
| SCHEMBL9269428 | 0.84 | GPR119 (0.47) | GPR119KDM4EBLMALOX15ALDH1A1 | |
| SCHEMBL9645077 | 0.84 | ALDH1A1 (0.41) | GPR119KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11995176 | 0.80 | CYP2C19 (0.41) | GPR119KDM4EBLMALDH1A1KMT2A | |
| SCHEMBL9718123 | 0.77 | GPR119 (0.41) | GPR119KDM4EBLMALOX15ALDH1A1 | |
| SCHEMBL30675171 | 0.76 | GPR119 (0.53) | GPR119KDM4EBLMALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545046-A1 | N-ACYL CYCLIC AMINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011111875-A1 | N-ACYL CYCLIC AMINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2011-09-15 | — | — | WO | disclosed |