Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.43 |
| ▸ | CHRNG | P07510 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460433 | 0.89 | GPR119 (0.45) | GPR119RIPK1ALDH1A1CHRNA7CHRNB2 | |
| SCHEMBL2460437 | 0.89 | GPR119 (0.45) | GPR119RIPK1ALDH1A1CHRNA7CHRNB2 | |
| SCHEMBL11995175 | 0.87 | ALDH1A1 (0.44) | GPR119RIPK1ALDH1A1CHRNA7CHRNB2 | |
| SCHEMBL5149946 | 0.85 | ABCB1 (0.52) | GPR119RIPK1KDM4EMEN1KMT2A | |
| SCHEMBL3857587 | 0.85 | ABCB1 (0.52) | GPR119RIPK1KDM4EMEN1KMT2A | |
| SCHEMBL475729 | 0.85 | ABCB1 (0.52) | GPR119RIPK1KDM4EMEN1KMT2A | |
| SCHEMBL9269428 | 0.84 | GPR119 (0.47) | GPR119RIPK1ALDH1A1CHRNA7CHRNB2 | |
| SCHEMBL11995176 | 0.82 | CYP2C19 (0.41) | GPR119RIPK1ALDH1A1KDM4ELMNA | |
| SCHEMBL9717959 | 0.81 | GPR119 (0.42) | GPR119ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL28528295 | 0.79 | RIPK1 (0.50) | GPR119RIPK1ALDH1A1TDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019618-A1 | PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-11-12 | — | — | WO | disclosed |
| US-5149704-A | Pyridyl- or thiazolidineaminesor ureas | ABBOTT LABORATORIES (US) | 1992-09-22 | — | — | US | disclosed |