Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | PPM1B | O75688 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24606310 | 0.86 | DOT1L (0.36) | DOT1LRIPK1 | |
| SCHEMBL24606327 | 0.85 | DOT1L (0.34) | DOT1L | |
| SCHEMBL24606280 | 0.84 | DOT1L (0.35) | DOT1L | |
| SCHEMBL26027103 | 0.84 | DOT1L (0.36) | DOT1LRIPK1 | |
| SCHEMBL24606262 | 0.84 | DOT1L (0.36) | DOT1LRIPK1 | |
| SCHEMBL26237796 | 0.83 | CSNK2A2 (0.35) | DOT1LCYP2C19 | |
| SCHEMBL25723098 | 0.83 | DOT1L (0.33) | DOT1L | |
| SCHEMBL24606316 | 0.83 | DOT1L (0.34) | DOT1LRIPK1 | |
| SCHEMBL20059148 | 0.82 | NPC1 (0.38) | NPC1DOT1LCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL24606256 | 0.82 | DOT1L (0.34) | DOT1LRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022142477-A1 | METHODS AND MODIFIED NUCLEOSIDES FOR TREATING CORONAVIRUS INFECTIONS | SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-07-07 | — | — | WO | disclosed |