Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19607818 | 0.85 | PDE5A (0.44) | SMN1; SMN2PDE5APDE4APDE4BPDE4C | |
| SCHEMBL19245876 | 0.80 | PDE5A (0.43) | SMN1; SMN2PDE5APDE4APDE4BPDE4C | |
| SCHEMBL18819577 | 0.74 | LMNA (0.35) | SMN1; SMN2PDE5APDE4APDE4BPDE4C | |
| SCHEMBL17682291 | 0.73 | ADORA2B (0.62) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18819578 | 0.71 | PDE5A (0.43) | SMN1; SMN2PDE5APDE4APDE4BPDE4C | |
| SCHEMBL19607816 | 0.71 | — | — | |
| SCHEMBL19245872 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2PDE5APDE4APDE4BPDE4C | |
| SCHEMBL19246013 | 0.68 | PDE5A (0.48) | SMN1; SMN2PDE5APDE4APDE4BPDE4C | |
| SCHEMBL17682258 | 0.68 | ADORA2B (0.56) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL17682292 | 0.64 | ADORA2B (0.62) | SMN1; SMN2PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49128-E1 | Hydroxyl purine compounds and applications thereof | Guangdong Raynovent Biotech Co., Ltd. (CN) | 2022-07-12 | — | — | US | disclosed |