Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16704033 | 0.79 | HTT (0.35) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL2099625 | 0.79 | ALDH1A1 (0.42) | SMN1; SMN2LMNAALDH1A1MAPTHTT | |
| SCHEMBL7449090 | 0.79 | KMT2A (0.36) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL7451066 | 0.77 | LMNA (0.46) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL7522327 | 0.77 | APOBEC3A (0.49) | KMT2ALMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7511907 | 0.77 | LMNA (0.43) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL7515229 | 0.76 | PDE10A (0.40) | KMT2ALMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL22336048 | 0.74 | RAB9A (0.39) | KMT2ASMN1; SMN2LMNAALDH1A1L3MBTL1 | |
| SCHEMBL1876572 | 0.74 | CNR2 (0.46) | KMT2AALDH1A1HTT | |
| SCHEMBL7461101 | 0.74 | HTT (0.42) | SMN1; SMN2ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3324977-B1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARM INC (US) | 2022-07-13 | — | — | EP | disclosed |