⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23984435 | 0.88 | FBP1 (0.34) | — | |
| SCHEMBL20329197 | 0.83 | — | — | |
| SCHEMBL26474203 | 0.83 | — | — | |
| SCHEMBL20334736 | 0.78 | — | — | |
| SCHEMBL13706079 | 0.76 | TLR4 (0.31) | — | |
| SCHEMBL26029385 | 0.76 | TLR4 (0.31) | — | |
| SCHEMBL22736772 | 0.76 | FBP1 (0.37) | — | |
| SCHEMBL27104772 | 0.75 | TLR4 (0.30) | — | |
| SCHEMBL19577789 | 0.74 | — | — | |
| SCHEMBL24211093 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11382981-B2 | Exon skipping oligomer conjugates for muscular dystrophy | SAREPTA THERAPEUTICS, INC. (US) | 2022-07-12 | — | — | US | disclosed |