Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 9/20 | 0.44 |
| ▸ | MMP1 | P03956 | 4/20 | 0.44 |
| ▸ | MMP3 | P08254 | 4/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13778778 | 0.83 | NAAA (0.58) | HPGDNAAAMMP2MMP1MMP3 | |
| SCHEMBL24332993 | 0.77 | TAAR1 (0.50) | POLBMMP1 | |
| SCHEMBL18375940 | 0.74 | FAAH (0.54) | MMP2MMP1MMP3 | |
| SCHEMBL23154665 | 0.74 | L3MBTL1 (0.65) | POLBMMP2MMP1MMP3 | |
| SCHEMBL23154817 | 0.74 | L3MBTL1 (0.65) | POLBMMP2MMP1MMP3 | |
| SCHEMBL23154816 | 0.74 | L3MBTL1 (0.65) | POLBMMP2MMP1MMP3 | |
| SCHEMBL27328049 | 0.73 | CHRNA1 (0.51) | TLR2 | |
| SCHEMBL19290164 | 0.73 | TAAR1 (0.46) | — | |
| SCHEMBL13136771 | 0.73 | CYP1A2 (0.56) | HPGDNAAAPOLBTLR2 | |
| SCHEMBL21585496 | 0.72 | FAAH (0.55) | HPGDNAAAMMP2MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150167-A2 | NOVEL MACROCYCLIC OPIOID PEPTIDES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-07-14 | — | — | WO | disclosed |