Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24614812 | 0.90 | TNKS (0.35) | TNKSTNKS2PTPN1KIF11ABCG2 | |
| SCHEMBL24614933 | 0.90 | TNKS (0.34) | TNKSTNKS2PTPN1KIF11 | |
| SCHEMBL24614705 | 0.89 | TNKS (0.41) | TNKSTNKS2PTPN1 | |
| SCHEMBL24614707 | 0.86 | ENPP1 (0.35) | TNKSTNKS2PTPN1 | |
| SCHEMBL24614709 | 0.85 | PTPN1 (0.34) | TNKSTNKS2PTPN1 | |
| SCHEMBL24614701 | 0.85 | PTPN1 (0.37) | TNKSTNKS2PTPN1 | |
| SCHEMBL24614725 | 0.84 | PTPN1 (0.36) | TNKSTNKS2PTPN1 | |
| SCHEMBL24614722 | 0.83 | PTPN1 (0.36) | TNKSTNKS2PTPN1 | |
| SCHEMBL24614938 | 0.83 | ALOX5 (0.35) | PTPN1 | |
| SCHEMBL24614700 | 0.82 | PTPN1 (0.35) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TMEM109, PIEZO1, L1CAM | TNKS 3531/4885TNKS2 3941/4885PTPN1 4341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.