SCHEMBL24614745

SCHEMBL24614745

c1ccc(-c2cc(-c3ccccc3)cc(-c3c4ccccc4c(-c4cc5ccc6oc7ccccc7c6c5c5c4oc4ccccc45)c4ccccc34)c2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC14B O60729 1/20 0.35
CDC14A Q9UNH5 1/20 0.35
ABCG2 Q9UNQ0 3/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1A2 P05177 1/20 0.35
FYN P06241 1/20 0.35
MAPK3 P27361 1/20 0.35
AHR P35869 1/20 0.35
PAX8 Q06710 1/20 0.35
KDM4E B2RXH2 5/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
MAPT P10636 4/20 0.34
HPGD P15428 4/20 0.34
PLA2G2A P14555 3/20 0.34
PLA2G4A P47712 3/20 0.34
CASP7 P55210 2/20 0.34
HSD17B10 Q99714 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24614907 0.97 CA1 (0.35) CDC14BCDC14AABCG2CYP1A1CYP1A2
SCHEMBL24614827 0.94 CDC14B (0.36) CDC14BCDC14AABCG2CYP1A1CYP1A2
SCHEMBL24614632 0.94 PLA2G2A (0.37) CDC14BCDC14AABCG2CYP1A1CYP1A2
SCHEMBL24614791 0.94 CA1 (0.38) CDC14BCDC14AABCG2CYP1A1CYP1A2
SCHEMBL24474566 0.93 CA1 (0.39) CDC14BCDC14AABCG2CYP1A1CYP1A2
SCHEMBL24614723 0.92 CA1 (0.38) CDC14BCDC14AABCG2CYP1A1CYP1A2
SCHEMBL24614779 0.92 CDC14B (0.38) CDC14BCDC14AABCG2KDM4EMEN1
SCHEMBL24614946 0.91 CA1 (0.38) CDC14BCDC14AABCG2CYP1A1CYP1A2
SCHEMBL24614814 0.91 CA1 (0.39) CDC14BCDC14AABCG2KDM4EMEN1
SCHEMBL24614646 0.91 HPGD (0.38) CDC14BCDC14AABCG2CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023139034-A1 ORGANIC ELECTRIC ELEMENT WITH MIXED HOST SYSTEM MERCK PATENT GMBH (DE) 2023-07-27 WO disclosed
US-20220223801-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220223801-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES TMEM109, PIEZO1, L1CAM CDC14B 4839/4885CDC14A 4804/4885ABCG2 4026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.