Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 6/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.44 |
| ▸ | CDK9 | P50750 | 5/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.36 |
| ▸ | TPX2 | Q9ULW0 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 3/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24615324 | 0.77 | CDK9 (0.44) | CSNK1DMAPK14CDK9CDC7PIM1 | |
| SCHEMBL31308619 | 0.76 | RIPK1 (0.51) | — | |
| SCHEMBL31240849 | 0.76 | CDK9 (0.44) | CDK9CDC7PIM1CCNT1AXL | |
| SCHEMBL24615543 | 0.76 | CSNK1D (0.38) | CSNK1DMAPK14CDK9MAPK11CCNT1 | |
| Hydrochloric Acid SCHEMBL29772841 | 0.75 | CSNK1D (0.39) | CSNK1DMAPK14CDK9MAPK11CCNT1 | |
| SCHEMBL24615544 | 0.75 | CDK9 (0.43) | MAPK14CDK9CDC7PIM1CCNT1 | |
| SCHEMBL20928262 | 0.74 | CSNK1D (0.40) | CSNK1DMAPK14CDK9CDC7PIM1 | |
| SCHEMBL24615534 | 0.74 | AURKA (0.56) | CDK9CDC7PIM1AURKAAURKB | |
| SCHEMBL31240552 | 0.72 | CDK9 (0.43) | MAPK14CDK9CDC7PIM1CCNT1 | |
| SCHEMBL23624650 | 0.70 | CDK9 (0.47) | CDK9CDC7PIM1CCNT1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150446-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2022-07-14 | — | — | WO | disclosed |