Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 14/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 13/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240849 | 0.79 | CDK9 (0.44) | CDK9CDC7PIM1CCNT1AXL | |
| SCHEMBL31240552 | 0.75 | CDK9 (0.43) | CDK9CDC7PIM1CCNT1AXL | |
| SCHEMBL24615533 | 0.75 | CSNK1D (0.44) | CDK9CDC7PIM1CCNT1AXL | |
| SCHEMBL31240630 | 0.72 | CDC7 (0.52) | CDK9CDC7PIM1AXLPRKCI | |
| SCHEMBL31240691 | 0.72 | CDK9 (0.52) | CDK9CDC7PIM1CCNT1AXL | |
| SCHEMBL24615324 | 0.72 | CDK9 (0.44) | CDK9CDC7PIM1CCNT1AXL | |
| SCHEMBL5538584 | 0.71 | CDK9 (0.40) | CDK9CDC7PIM1CCNT1AXL | |
| SCHEMBL16041244 | 0.70 | CDC7 (0.59) | CDK9CDC7PIM1AXLPRKCI | |
| SCHEMBL31240848 | 0.70 | CDC7 (0.59) | CDK9CDC7PIM1AXLPRKCI | |
| SCHEMBL31240593 | 0.70 | CDC7 (0.59) | CDK9CDC7PIM1AXLPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150446-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2022-07-14 | — | — | WO | disclosed |