Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 8/20 | 0.40 |
| ▸ | JAK2 | O60674 | 7/20 | 0.40 |
| ▸ | TYK2 | P29597 | 7/20 | 0.40 |
| ▸ | JAK3 | P52333 | 5/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.34 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.33 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24615424 | 0.89 | TYK2 (0.41) | JAK1JAK2TYK2JAK3MCHR1 | |
| SCHEMBL24615601 | 0.88 | TYK2 (0.41) | JAK1JAK2TYK2JAK3SMARCA2 | |
| SCHEMBL24615420 | 0.88 | TYK2 (0.41) | JAK1JAK2TYK2JAK3SMARCA2 | |
| SCHEMBL29772821 | 0.88 | JAK1 (0.40) | JAK1JAK2TYK2JAK3MCHR1 | |
| SCHEMBL24615598 | 0.88 | JAK1 (0.42) | JAK1JAK2TYK2JAK3KIT | |
| SCHEMBL29772862 | 0.86 | JAK1 (0.44) | JAK1JAK2TYK2JAK3SMARCA2 | |
| SCHEMBL24615583 | 0.86 | JAK1 (0.44) | JAK1JAK2TYK2JAK3SMARCA2 | |
| SCHEMBL24615433 | 0.82 | JAK2 (0.49) | JAK1JAK2TYK2JAK3KIT | |
| SCHEMBL24615367 | 0.82 | TYK2 (0.42) | JAK1JAK2TYK2JAK3KIT | |
| SCHEMBL24615368 | 0.82 | TYK2 (0.41) | JAK1JAK2TYK2JAK3KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150446-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2022-07-14 | — | — | WO | disclosed |