Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24616776 | 0.85 | ALDH1A1 (0.36) | ALDH1A1KDM4ERAB9ASMN1; SMN2HCAR2 | |
| SCHEMBL29676887 | 0.81 | RAB9A (0.36) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL24616682 | 0.81 | RAB9A (0.36) | ALDH1A1RAB9ASMN1; SMN2NPC1MAPT | |
| SCHEMBL24616690 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KDM4ESMN1; SMN2HCAR2LMNA | |
| SCHEMBL29395403 | 0.78 | KMT2A (0.34) | TSHR | |
| SCHEMBL24616755 | 0.78 | KMT2A (0.34) | TSHR | |
| SCHEMBL24397858 | 0.74 | ALDH1A1 (0.36) | ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL17894135 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL17894159 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9936063 | 0.70 | ALDH1A1 (0.44) | ALDH1A1KDM4ERAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022038365-A9 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | claimed |
| EP-4200275-A2 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | Sitryx Therapeutics Limited (GB) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022038365-A9 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022038365-A9 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022038365-A2 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2022-02-24 | — | — | WO | disclosed |