Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24616793 | 0.85 | HSD11B1 (0.38) | ALDH1A1MAPTHCAR2L3MBTL1MEN1 | |
| SCHEMBL24616798 | 0.83 | HCAR2 (0.36) | ALDH1A1HCAR2 | |
| SCHEMBL24616758 | 0.82 | APP (0.37) | ALDH1A1LMNASMN1; SMN2HDAC1MEN1 | |
| SCHEMBL24616687 | 0.82 | CA1 (0.35) | ALDH1A1MAPTHCAR2LMNAL3MBTL1 | |
| SCHEMBL24616783 | 0.80 | KMT2A (0.48) | ALDH1A1POLBKMT2A | |
| SCHEMBL24616754 | 0.80 | ALDH1A1 (0.36) | ALDH1A1MAPTHCAR2LMNASMN1; SMN2 | |
| SCHEMBL24616779 | 0.77 | HCAR2 (0.37) | HCAR2 | |
| SCHEMBL3813595 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MAPTMAPK1LMNAL3MBTL1 | |
| SCHEMBL27970983 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPTMAPK1LMNAL3MBTL1 | |
| SCHEMBL24616777 | 0.75 | HCAR2 (0.33) | ALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022038365-A9 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | claimed |
| WO-2022038365-A9 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022038365-A9 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |