Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24387633 | 1.00 | HTT (0.51) | HTTALDH1A1KMT2AATML3MBTL1 | |
| SCHEMBL6154504 | 0.89 | ALDH1A1 (0.51) | HTTALDH1A1KMT2AATML3MBTL1 | |
| SCHEMBL5317083 | 0.89 | ALDH1A1 (0.51) | HTTALDH1A1KMT2AATMLDHA | |
| SCHEMBL7360535 | 0.86 | ALDH1A1 (0.49) | HTTALDH1A1KMT2AATML3MBTL1 | |
| SCHEMBL7360527 | 0.86 | ALDH1A1 (0.49) | HTTALDH1A1KMT2AATML3MBTL1 | |
| SCHEMBL7669900 | 0.84 | ALDH1A1 (0.51) | HTTALDH1A1KMT2AATML3MBTL1 | |
| SCHEMBL8992132 | 0.84 | LDHA (0.53) | HTTALDH1A1KMT2AATML3MBTL1 | |
| SCHEMBL2574460 | 0.84 | ALDH1A1 (0.51) | HTTALDH1A1KMT2AATML3MBTL1 | |
| SCHEMBL14517244 | 0.84 | ALDH1A1 (0.48) | HTTALDH1A1KMT2AATML3MBTL1 | |
| SCHEMBL20346809 | 0.84 | LDHA (0.53) | HTTALDH1A1KMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022038365-A9 | FUMARATE DERIVATIVES AND THEIR MEDICAL USE | SITRYX THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |