Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FABP7 | O15540 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20346809 | 1.00 | LDHA (0.53) | LDHAATMALDH1A1NPC1POLB | |
| SCHEMBL7360535 | 0.89 | ALDH1A1 (0.49) | LDHAATMALDH1A1NPC1POLB | |
| SCHEMBL7360527 | 0.89 | ALDH1A1 (0.49) | LDHAATMALDH1A1NPC1POLB | |
| SCHEMBL2574460 | 0.88 | ALDH1A1 (0.51) | LDHAATMALDH1A1NPC1POLB | |
| SCHEMBL14517244 | 0.88 | ALDH1A1 (0.48) | LDHAATMALDH1A1NPC1POLB | |
| SCHEMBL7669900 | 0.88 | ALDH1A1 (0.51) | LDHAATMALDH1A1NPC1POLB | |
| SCHEMBL5317083 | 0.86 | ALDH1A1 (0.51) | LDHAATMALDH1A1NPC1POLB | |
| SCHEMBL24387633 | 0.84 | HTT (0.51) | LDHAATMALDH1A1NPC1POLB | |
| SCHEMBL24616786 | 0.84 | HTT (0.51) | LDHAATMALDH1A1NPC1POLB | |
| SCHEMBL4900863 | 0.84 | SLC15A1 (0.59) | ATMALDH1A1KMT2AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510378-A | Retroviral protease inhibitors | G.D. SEARLE & CO. (US) | 1996-04-23 | — | — | US | disclosed |