Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15181275 | 0.69 | MEN1 (0.47) | MEN1GAARAB9AKMT2AALDH1A1 | |
| SCHEMBL6520641 | 0.67 | MEN1 (0.46) | MEN1GAARAB9AKMT2AALDH1A1 | |
| SCHEMBL18810171 | 0.67 | POLB (0.50) | MEN1GAARAB9AKMT2AALDH1A1 | |
| SCHEMBL20680187 | 0.66 | MEN1 (0.41) | MEN1GAARAB9AKMT2AALDH1A1 | |
| SCHEMBL4905639 | 0.65 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1CASP3MAPT | |
| SCHEMBL8091163 | 0.65 | CASP3 (0.59) | MEN1KMT2AALDH1A1CASP3POLB | |
| SCHEMBL7185886 | 0.65 | CASP3 (0.59) | MEN1KMT2AALDH1A1CASP3POLB | |
| SCHEMBL28695770 | 0.64 | ALDH1A1 (0.40) | ALDH1A1DRD3MAPTPOLBMAOB | |
| SCHEMBL1512469 | 0.64 | CA12 (0.46) | MEN1GAARAB9AKMT2AALDH1A1 | |
| SCHEMBL873778 | 0.63 | CASP3 (0.52) | MEN1RAB9AKMT2AALDH1A1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149167-A1 | DIAMINOPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBONITRILE COMPOUNDS AS ADENOSINE 2A RECEPTOR AND ADENOSINE 2B RECEPTOR ANTAGONIST | BUGWORKS RESEARCH INDIA PVT LTD (IN) | 2022-07-14 | — | — | WO | disclosed |