Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | CCR1 | P32246 | 3/20 | 0.40 |
| ▸ | CCR8 | P51685 | 3/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 3/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24619738 | 0.90 | RPS6KA5 (0.42) | ADORA2AADORA3ADORA1L3MBTL1CCR1 | |
| SCHEMBL29727041 | 0.83 | ADORA2A (0.46) | ADORA2AADORA3ADORA1L3MBTL1KDM4E | |
| SCHEMBL24619110 | 0.83 | ADORA2A (0.46) | ADORA2AADORA3ADORA1L3MBTL1KDM4E | |
| SCHEMBL24619744 | 0.80 | NPC1 (0.56) | ADORA2ARPS6KA5ALDH1A1KDM4ENPC1 | |
| SCHEMBL24619269 | 0.79 | CCR1 (0.34) | ADORA2ACCR1CCR8ALDH1A1RAB9A | |
| SCHEMBL24619598 | 0.77 | CCR1 (0.43) | ADORA2AADORA3ADORA1L3MBTL1CCR1 | |
| SCHEMBL3718956 | 0.76 | KDM4E (0.46) | ADORA2AADORA3ADORA1L3MBTL1CCR1 | |
| SCHEMBL29931718 | 0.74 | PDGFRB (0.47) | NPC1RAB9AMAPTMTOR | |
| SCHEMBL27029564 | 0.74 | PDGFRB (0.47) | NPC1RAB9AMAPTMTOR | |
| SCHEMBL19966317 | 0.73 | ALDH1A1 (0.36) | ADORA2AL3MBTL1RPS6KA5ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149057-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-07-14 | — | — | WO | disclosed |
| WO-2022149057-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-07-14 | — | — | WO | disclosed |