Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PRNP | P04156 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11669167 | 0.89 | ALDH1A1 (0.71) | ALDH1A1KDM4EGAAATMHTT | |
| SCHEMBL16974161 | 0.86 | ALDH1A1 (0.72) | ALDH1A1KDM4EGAAATMHTT | |
| SCHEMBL30758183 | 0.83 | L3MBTL1 (0.72) | ALDH1A1KDM4EGAAATMHTT | |
| SCHEMBL5809940 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4EGAAATMRXFP1 | |
| SCHEMBL5810083 | 0.81 | ATM (0.79) | ALDH1A1KDM4EGAAATMRXFP1 | |
| SCHEMBL13210156 | 0.81 | GAA (0.59) | ALDH1A1KDM4EGAAATMNPC1 | |
| SCHEMBL30251658 | 0.81 | GAA (0.59) | ALDH1A1KDM4EGAAATMNPC1 | |
| SCHEMBL13392288 | 0.80 | ALDH1A1 (0.71) | ALDH1A1KDM4EGAAATMHTT | |
| SCHEMBL24619141 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4EGAAATMHTT | |
| SCHEMBL13209744 | 0.78 | L3MBTL1 (0.69) | ALDH1A1KDM4EGAAHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149057-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-07-14 | — | — | WO | disclosed |