Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25217075 | 0.88 | ALDH1A1 (1.00) | ATMALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL30758183 | 0.86 | L3MBTL1 (0.72) | ATMALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL24951547 | 0.83 | TSHR (0.61) | ATMALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL11669167 | 0.82 | ALDH1A1 (0.71) | ATMALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL31133520 | 0.81 | KDM4E (0.72) | ALDH1A1KDM4EGAAL3MBTL1HPGD | |
| SCHEMBL5810312 | 0.81 | KDM4E (0.72) | ALDH1A1KDM4EGAAL3MBTL1HPGD | |
| SCHEMBL24619210 | 0.81 | ALDH1A1 (0.69) | ATMALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL7365268 | 0.81 | ALDH1A1 (0.66) | ATMALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL2000832 | 0.81 | SMN1; SMN2 (0.62) | ATMALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL31510551 | 0.81 | ALDH1A1 (0.66) | ATMALDH1A1SMN1; SMN2KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745291-A | N- (2- (4-cyanothiazolidin-3-yl) -2-oxoethyl) -quinoline-4-carboxamide | 阿斯利康(瑞典)有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2006136008-A1 | SALICYLIC ACID HYDRAZONES AS INHIBITORS OF THE ERK MAPKINASE PATHWAY AND FOR THE TREATMENT OF CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2006-12-28 | — | — | WO | disclosed |