Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727266 | 1.00 | SLC40A1 (0.36) | SLC40A1EGFRROCK1GSK3AGSK3B | |
| SCHEMBL29727230 | 0.86 | PSMD14 (0.42) | SLC40A1EGFRROCK1GSK3AGSK3B | |
| SCHEMBL24619157 | 0.86 | PSMD14 (0.42) | SLC40A1EGFRROCK1GSK3AGSK3B | |
| SCHEMBL24619188 | 0.86 | KDM4E (0.39) | EGFRROCK1GSK3AGSK3BPDGFRB | |
| SCHEMBL29727236 | 0.86 | KDM4E (0.39) | EGFRROCK1GSK3AGSK3BPDGFRB | |
| SCHEMBL20392650 | 0.78 | LPL (0.39) | EGFRROCK1GSK3AGSK3BPDGFRB | |
| SCHEMBL24619654 | 0.76 | SLC40A1 (0.43) | SLC40A1GSK3AGSK3BGAAALOX5AP | |
| SCHEMBL15594472 | 0.76 | ROCK1 (0.46) | EGFRROCK1GAAPRMT5WDR77 | |
| SCHEMBL24619214 | 0.75 | SLC40A1 (0.42) | SLC40A1GSK3AGSK3BGAAALOX5AP | |
| SCHEMBL24619607 | 0.75 | EGFR (0.35) | EGFRROCK1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149057-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-07-14 | — | — | WO | disclosed |