SCHEMBL2461981

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15702514	0.80	HPGD (0.44)	HPGDALDH1A1KDM4EGAAMEN1
	SCHEMBL2463055	0.79	MAPT (0.50)	HPGDALDH1A1KDM4EGAAMEN1
	SCHEMBL11397912	0.77	HPGD (0.42)	HPGDALDH1A1KDM4EGAAMEN1
	SCHEMBL2460931	0.75	KDM4E (0.50)	HPGDALDH1A1KDM4EGAAMEN1
	SCHEMBL1701703	0.75	HTR2C (0.69)	HTR2AHTR2CHTR2BKDM4EMAPT
	SCHEMBL1136112	0.72	HPGD (0.39)	HTR2AHTR2CHTR2BHPGDALDH1A1
	SCHEMBL11483709	0.71	SLC2A1 (0.36)	HTR2AHTR2CHTR2BHPGDALDH1A1
	SCHEMBL9621241	0.71	HSD17B1 (0.45)	MEN1KMT2A
	SCHEMBL6164757	0.71	HTR2C (0.69)	HTR2AHTR2CHTR2BKDM4EMAPT
	SCHEMBL646557	0.70	MAOB (0.44)	HTR2AHTR2CHTR2BGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.