SCHEMBL2461998

SCHEMBL2461998

C=C(C(=O)O)C(Cl)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.47
CYP2D6 P10635 1/20 0.43
SRC P12931 1/20 0.43
TSHR P16473 1/20 0.42
LMNA P02545 6/20 0.41
MAPK1 P28482 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CTSD P07339 1/20 0.41
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
NPSR1 Q6W5P4 3/20 0.40
MAPT P10636 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
XBP1 P17861 1/20 0.39
ATM Q13315 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL585336 0.82 CTSD (0.54) HPGDCYP2D6SRCLMNAMAPK1
SCHEMBL6993309 0.79 HPGD (0.44) HPGDCYP2D6SRCTSHRLMNA
SCHEMBL11106650 0.79 ALDH1A1 (0.39) HPGDTSHRLMNAMAPK1ALDH1A1
SCHEMBL27533616 0.79 KMT2A (0.47) HPGDCYP2D6TSHRLMNAMAPK1
SCHEMBL9860991 0.77 CYP2D6 (0.46) HPGDCYP2D6SRCTSHRLMNA
SCHEMBL5050305 0.77 CES2 (0.48) HPGDCYP2D6SRCTSHRLMNA
SCHEMBL9181806 0.77 CYP2D6 (0.50) HPGDCYP2D6SRCTSHRLMNA
SCHEMBL664900 0.77 SRC (0.56) HPGDCYP2D6SRCTSHRLMNA
SCHEMBL5325296 0.77 SRC (0.56) HPGDCYP2D6SRCTSHRLMNA
SCHEMBL2971437 0.76 HPGD (0.70) HPGDCYP2D6SRCLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4192821-A1 ALPHA,BETA UNSATURATED METHACRYLIC ESTERS WITH ANTI-INFLAMMATORY PROPERTIES Sitryx Therapeutics Limited (GB) 2023-06-14 EP disclosed
US-8012668-B2 Planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-20080206675-A1 Support with hydrophilic polymer bonded to support by crosslinking and image forming layer FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
EP-1577087-B1 Planographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2007-01-17 EP disclosed
US-20060246372-A1 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2006-11-02 US disclosed
EP-1577087-A2 Planographic printing plate precursor Fuji Photo Film Co. Ltd. (JP) 2005-09-21 EP disclosed