Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25576017 | 0.99 | NAAA (0.52) | NAAAHPGDSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL25575775 | 0.95 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL17652562 | 0.86 | HDAC1 (0.54) | SMN1; SMN2RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL17661235 | 0.85 | HDAC1 (0.49) | SMN1; SMN2RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL19747788 | 0.85 | MEN1 (0.53) | SMN1; SMN2RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL17652621 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL19747112 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL17874030 | 0.82 | MAPT (0.56) | HPGDSMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL13901842 | 0.82 | FAAH (0.61) | HPGDSMN1; SMN2RAB9AMEN1ALDH1A1 | |
| SCHEMBL17652550 | 0.82 | MEN1 (0.55) | SMN1; SMN2RAB9AMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148821-A1 | USP7 BINDING SURVIVAL-TARGETING CHIMERIC (SURTAC) MOLECULES & USES THEREOF | LOCKI THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |