Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11026230 | 0.76 | KDM4E (0.34) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL1945331 | 0.65 | KDM4E (0.64) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL20865055 | 0.65 | ALDH1A1 (0.46) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL19987789 | 0.62 | EPHX2 (0.30) | — | |
| SCHEMBL3604453 | 0.62 | MAPT (0.30) | MAPT | |
| SCHEMBL6028175 | 0.61 | KDM4E (0.43) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11293666 | 0.61 | KDM4E (0.36) | KDM4EALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7559507 | 0.60 | TYMP (0.37) | — | |
| SCHEMBL1063543 | 0.60 | ADORA2A (0.40) | MEN1KMT2ALMNA | |
| SCHEMBL2462137 | 0.60 | PDE4A (0.69) | KDM4EALDH1A1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106047-A1 | METHOD FOR DETERMINING THE THROMBOCYTE FUNCTION OF THE BLOOD | VDG-VON DER GOLTZ GMBH (DE) | 2009-09-03 | — | — | WO | claimed |
| EP-2552471-A1 | NOVEL PEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | ELI LILLY AND COMPANY (US) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011119657-A1 | NOVEL PEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | ELI LILLY AND COMPANY (US) | 2011-09-29 | — | — | WO | disclosed |
| WO-2010007382-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HSTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED. (JP) | 2010-01-21 | — | — | WO | disclosed |