Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3604452 | 0.62 | MEN1 (0.54) | — | |
| SCHEMBL2462138 | 0.62 | KDM4E (0.40) | MAPT | |
| SCHEMBL3177931 | 0.61 | ADORA2A (0.42) | MAPTATM | |
| SCHEMBL11026230 | 0.60 | KDM4E (0.34) | MAPT | |
| SCHEMBL1943360 | 0.60 | MAPT (0.47) | MAPTATM | |
| SCHEMBL19987789 | 0.58 | EPHX2 (0.30) | — | |
| SCHEMBL8354784 | 0.56 | TSHR (0.38) | MAPTATM | |
| SCHEMBL3180033 | 0.56 | ADORA2A (0.40) | — | |
| SCHEMBL1944737 | 0.56 | MAPT (0.43) | MAPTATM | |
| SCHEMBL6295463 | 0.54 | PARP1 (0.50) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160354-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160354-A1 | NOVEL COMPOUNDS | HCAR1, XDH, GPR84 | MAPT 3754/4885ATM 3893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.