Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31580150 | 0.89 | HPGD (0.45) | ALDH1A1CYP3A4HPGDTDP1HIF1A | |
| SCHEMBL13662232 | 0.86 | MAPT (0.47) | ALDH1A1CYP3A4HPGDTDP1HIF1A | |
| SCHEMBL16865784 | 0.81 | TDP1 (0.56) | ALDH1A1CYP3A4HPGDTDP1HIF1A | |
| SCHEMBL30335042 | 0.81 | TDP1 (0.56) | ALDH1A1CYP3A4HPGDTDP1HIF1A | |
| SCHEMBL18680082 | 0.78 | CYP3A4 (0.53) | ALDH1A1CYP3A4HPGDTDP1HIF1A | |
| SCHEMBL23753349 | 0.77 | ALDH1A1 (0.42) | ALDH1A1CYP3A4HPGDTDP1HIF1A | |
| SCHEMBL31430664 | 0.77 | ALDH1A1 (0.42) | ALDH1A1CYP3A4HPGDTDP1HIF1A | |
| SCHEMBL23753327 | 0.76 | HPGD (0.41) | ALDH1A1CYP3A4HPGDTDP1HIF1A | |
| SCHEMBL31430683 | 0.76 | HPGD (0.41) | ALDH1A1CYP3A4HPGDTDP1HIF1A | |
| SCHEMBL16745253 | 0.74 | HPGD (0.48) | ALDH1A1CYP3A4HPGDTDP1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220373-A1 | FLUORESCENT PROBES FOR MONOACYLGLYCEROL LIPASE (MAGL) | HOFFMANN-LA ROCHE INC. (US) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220373-A1 | FLUORESCENT PROBES FOR MONOACYLGLYCEROL LIPASE (MAGL) | MGLL, LPL, LIPA | ALDH1A1 846/4885CYP3A4 1300/4885HPGD 3548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.