SCHEMBL24622650

SCHEMBL24622650

c1ccc2c(c1)-c1ccc(-c3c4ccccc4c(-c4ccc(-c5ccc6oc7ccccc7c6c5)cc4)c4ccccc34)cc1C21C2CC3CC(C2)CC1C3

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.32
HSP90AB1 P08238 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
LMNA P02545 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
CXCR3 P49682 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24622798 0.97 HSP90AA1 (0.34) HSP90AA1HSP90AB1ALDH1A1MAPTLMNA
SCHEMBL24622643 0.94 NPC1 (0.32) ALDH1A1MAPTLMNAKDM4EMEN1
SCHEMBL24622685 0.94 NPC1 (0.32) ALDH1A1MAPTLMNAKDM4EMEN1
SCHEMBL24622696 0.94 PLA2G2A (0.37) HSP90AA1HSP90AB1ALDH1A1MAPTLMNA
SCHEMBL24622835 0.90 ALDH1A1 (0.36) HSP90AA1HSP90AB1ALDH1A1MAPTLMNA
SCHEMBL24622569 0.90 AHR (0.33) ALDH1A1MAPTLMNAKDM4EMEN1
SCHEMBL23626258 0.89 PDK2 (0.39) ALDH1A1MAPTLMNAKDM4EMEN1
SCHEMBL25614658 0.88 ALDH1A1 (0.34) HSP90AA1HSP90AB1ALDH1A1MAPTLMNA
SCHEMBL25614609 0.87 KDM4E (0.30) ALDH1A1MAPTKDM4EHPGD
SCHEMBL23606115 0.87 PLA2G2A (0.34) HSP90AA1HSP90AB1ALDH1A1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220220049-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220220049-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS HCN2, EPCAM, EFNA1 HSP90AA1 3240/4885HSP90AB1 4366/4885ALDH1A1 487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.