Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.34 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | BMP1 | P13497 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | GGH | Q92820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23289285 | 0.82 | PSMB5 (0.42) | FOLH1NAALAD2RIMKLAPSMB5KEAP1 | |
| SCHEMBL25128148 | 0.79 | PSMB5 (0.47) | FOLH1NAALAD2RIMKLAPSMB5KEAP1 | |
| SCHEMBL25129090 | 0.77 | FOLH1 (0.40) | FOLH1NAALAD2RIMKLABMP1GGH | |
| SCHEMBL26173989 | 0.73 | FOLH1 (0.47) | FOLH1NAALAD2RIMKLACYP1A2BMP1 | |
| SCHEMBL19681930 | 0.71 | BMP1 (0.39) | FOLH1NAALAD2RIMKLAKEAP1BMP1 | |
| SCHEMBL12094213 | 0.70 | NOD1 (0.41) | FOLH1PLA2G10NOD1PLA2G2C | |
| SCHEMBL468800 | 0.69 | FOLH1 (0.59) | FOLH1NAALAD2RIMKLANOD1GGH | |
| SCHEMBL12648688 | 0.69 | FOLH1 (0.59) | FOLH1NAALAD2RIMKLANOD1GGH | |
| SCHEMBL468801 | 0.69 | FOLH1 (0.59) | FOLH1NAALAD2RIMKLANOD1GGH | |
| SCHEMBL20131935 | 0.69 | FOLH1 (0.33) | FOLH1NAALAD2RIMKLAKEAP1BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150637-A1 | NOVEL STEROID PAYLOADS, STEROID LINKERS, ADCs CONTAINING AND USE THEREOF | IMMUNEXT, INC. (US) | 2022-07-14 | — | — | WO | disclosed |