Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | GCGR | P47871 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.55 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462294 | 1.00 | PTPN5 (0.71) | PTPN5ALDH1A1HPGDPOLBLMNA | |
| SCHEMBL3914250 | 0.81 | THRB (0.58) | PTPN5ALDH1A1HPGDPOLBLMNA | |
| SCHEMBL3914245 | 0.81 | THRB (0.58) | PTPN5ALDH1A1HPGDPOLBLMNA | |
| SCHEMBL2648282 | 0.81 | ALDH1A1 (0.68) | ALDH1A1HPGDPOLBLMNAGAA | |
| SCHEMBL14581045 | 0.79 | GCGR (0.63) | ALDH1A1HPGDPOLBLMNAGAA | |
| SCHEMBL919327 | 0.78 | THRB (0.59) | PTPN5ALDH1A1HPGDPOLBLMNA | |
| SCHEMBL919329 | 0.78 | THRB (0.59) | PTPN5ALDH1A1HPGDPOLBLMNA | |
| SCHEMBL2649089 | 0.76 | POLB (0.66) | ALDH1A1HPGDPOLBLMNAGAA | |
| SCHEMBL20248982 | 0.75 | MAPT (0.78) | ALDH1A1HPGDPOLBLMNAGAA | |
| SCHEMBL2649274 | 0.75 | GCGR (0.76) | PTPN5ALDH1A1HPGDPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367522-A2 | METHOD AND COMPOSITION FOR SKIN COLOR MODULATION | Unilever Plc, A Company Registered In England And Wales under company no. 41424 of Unilever House (GB) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010072805-A2 | METHOD AND COMPOSITION FOR COLOR MODULATION | UNILEVER PLC (GB) | 2010-07-01 | — | — | WO | disclosed |
| US-20100158829-A1 | Method and Composition for Color Modulation | CONOPCO, INC., D/B/A UNILEVER (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158829-A1 | Method and Composition for Color Modulation | TYR, TH, COMT | PTPN5 956/4885ALDH1A1 2383/4885HPGD 1098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.