Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 4/20 | 0.59 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.59 |
| ▸ | KDM1A | O60341 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940968 | 0.90 | HSD17B2 (0.72) | HSD17B2HSD17B1KDM1AMAOAMAOB | |
| SCHEMBL10212283 | 0.90 | HSD17B2 (0.72) | HSD17B2HSD17B1KDM1AMAOAMAOB | |
| SCHEMBL18774006 | 0.90 | HSD17B2 (0.60) | HSD17B2HSD17B1KDM1AMAOAMAOB | |
| SCHEMBL9001650 | 0.89 | MAOA (0.63) | HSD17B2KDM1AMAOAMAOBHPGD | |
| SCHEMBL23367854 | 0.85 | GPBAR1 (0.55) | HSD17B2HSD17B1HPGDKDM4EKMT2A | |
| SCHEMBL18773818 | 0.85 | SMN1; SMN2 (0.55) | HSD17B2HSD17B1KDM1AMAOAMAOB | |
| SCHEMBL5549839 | 0.84 | HPGD (0.57) | HSD17B2HSD17B1HPGDKMT2ATDP1 | |
| SCHEMBL32688152 | 0.84 | KDM1A (0.58) | HSD17B2KDM1AMAOAMAOBHPGD | |
| Water SCHEMBL11233105 | 0.84 | HSD17B2 (0.50) | HSD17B2HSD17B1KDM1AMAOAMAOB | |
| Water SCHEMBL11235271 | 0.84 | HSD17B2 (0.50) | HSD17B2HSD17B1KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024295-B | Photo-induced amide dealkylation method and application thereof | 广州中医药大学(广州中医药研究院) | 2025-06-13 | — | — | CN | disclosed |
| CN-117024295-A | Photo-induced amide dealkylation method and application thereof | 广州中医药大学(广州中医药研究院) | 2023-11-10 | — | — | CN | disclosed |
| EP-1773786-B1 | FIVE-MEMBERED HETEROCYCLES USEFUL AS SERINE PROTEASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-04-26 | — | — | EP | disclosed |
| US-8410303-B2 | Direct conversion of phenols into amides and esters of benzoic acid | The Florida State University Research Foundation, Inc. (US) | 2013-04-02 | — | — | US | disclosed |
| US-8410303-B2 | Direct conversion of phenols into amides and esters of benzoic acid | The Florida State University Research Foundation, Inc. (US) | 2013-04-02 | — | — | US | disclosed |
| US-8410303-B2 | Direct conversion of phenols into amides and esters of benzoic acid | The Florida State University Research Foundation, Inc. (US) | 2013-04-02 | — | — | US | disclosed |
| US-20120289502-A1 | IMIDAZOLE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-11-15 | — | — | US | disclosed |
| US-8273738-B2 | Imidazole derivatives | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-8273738-B2 | Imidazole derivatives | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20110237798-A1 | DIRECT CONVERSION OF PHENOLS INTO AMIDES AND ESTERS OF BENZOIC ACID | The Florida State University Research Foundation, Inc. (US) | 2011-09-29 | — | — | US | disclosed |
| US-20110237798-A1 | DIRECT CONVERSION OF PHENOLS INTO AMIDES AND ESTERS OF BENZOIC ACID | The Florida State University Research Foundation, Inc. (US) | 2011-09-29 | — | — | US | disclosed |
| US-20110237798-A1 | DIRECT CONVERSION OF PHENOLS INTO AMIDES AND ESTERS OF BENZOIC ACID | The Florida State University Research Foundation, Inc. (US) | 2011-09-29 | — | — | US | disclosed |
| US-20100152178-A1 | IMIDAZOLE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100152178-A1 | IMIDAZOLE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-06-17 | — | — | US | disclosed |
| EP-2090570-A1 | IMIDAZOLE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237798-A1 | DIRECT CONVERSION OF PHENOLS INTO AMIDES AND ESTERS OF BENZOIC ACID | DDC, NISCH, TST | HSD17B2 2112/4885HSD17B1 1685/4885KDM1A 842/4885 |
| US-20120289502-A1 | IMIDAZOLE DERIVATIVES | CNR1, CNR2, ARRB1 | HSD17B2 1381/4885HSD17B1 1726/4885KDM1A 1903/4885 |
| US-20100152178-A1 | IMIDAZOLE DERIVATIVES | CNR1, CNR2, ARRB1 | HSD17B2 1381/4885HSD17B1 1726/4885KDM1A 1903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.