SCHEMBL24624701

SCHEMBL24624701

CNCCN1C(=O)CC(N)C1=O

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 5/20 0.36
ALDH1A1 P00352 6/20 0.35
TP53 P04637 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CARM1 Q86X55 2/20 0.32
PRMT6 Q96LA8 2/20 0.32
PRMT8 Q9NR22 2/20 0.32
PRMT1 Q99873 1/20 0.32
GAA P10253 1/20 0.31
AADAT Q8N5Z0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10028023 0.80 CARM1 (0.36) CYP19A1ALDH1A1HTTMEN1KMT2A
SCHEMBL14275616 0.79 CYP19A1 (0.53) CYP19A1ALDH1A1TP53MAPTHPGD
SCHEMBL24235572 0.79 CYP19A1 (0.33) CYP19A1ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL18471609 0.77 CYP19A1 (0.36) CYP19A1ALDH1A1TP53MAPTHPGD
SCHEMBL13318044 0.76 POLB (0.35) CYP19A1ALDH1A1HTTMEN1KMT2A
SCHEMBL17232559 0.76 TSHR (0.35) CYP19A1ALDH1A1HPGDHTTMEN1
SCHEMBL24235519 0.76 CYP19A1 (0.31) CYP19A1ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL2853909 0.76 LMNA (0.36) CYP19A1ALDH1A1TP53MAPTHPGD
SCHEMBL2853911 0.76 LMNA (0.36) CYP19A1ALDH1A1TP53MAPTHPGD
SCHEMBL2687595 0.75 GAA (0.38) CYP19A1ALDH1A1TP53MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022148887-A1 HYDROGELS FOR CELL THERAPY ADOCIA (FR) 2022-07-14 WO disclosed